estrange[i'streindʒ]

• vt.
  • 使疏远；离间；使失和(from)：

    Their quarrel estranged the two friends.

    他们的争吵使两个朋友失和。

  • 使隔离，使远离，使脱离，使离开(熟悉的环境、亲友或相关物)(from):

    The necessity for traveling on business has estranged her from her family.

    她因必须出差而一直离开亲人。

  • 使转手；使作别用，转作他用
• 变形:

  vt.estranged.estranging